Tablet Presentation

Each Film Coated Tablet Contains:
Phenytoin Sodium IP 100 mg

Phenytoin is the antiepileptic drug. It belongs to the hydantoin group of class.

Indications

• It is used to treat seizures occurring during the neurosurgery
• It is used in tonic clonic seizures

Mechanism of action

Phenytoin mainly blocks the voltage gated sodium channel which generates the high frequency action potentials of neurons

Pharmacokinetics

Absorption- It is orally absorbed
Protein binding– It is about 90% bound to plasma proteins
Metabolism– It is metabolized into the reactive arene oxides intermediate
Excretion- It is excreted unchanged in the urine

Side Effects

• Headache
• Nausea
• Vomiting
• Constipation
• Nervousness

Contraindication

• Contraindicated in people with known hypersensitivity
• Contraindicated in the Adams stoke syndrome
• Contraindicated in pregnancy

Storage

Store it at room temperature.